LINACS
LINACS Home
OligoCare
Back to Lazertinib
Source Articles

Lazertinib

Showing 1 study arm with grade ≥3 adverse event data (treatment-related and RT-related). Click a column header to sort.
Note on patient counts: some articles reported only percentages rather than absolute numbers. Where this occurred, the number of patients — including those with grade ≥3 adverse events — was derived by applying the reported percentage to the total arm size, which may produce a non-integer value. These figures have been rounded to the nearest integer for display.
1st Author⇅ Year⇅ Study Type⇅ Title⇅ DOI⇅ clinical trial number⇅ number of patients⇅ median/mean age⇅ median follow-up [months]⇅ tumor type⇅ treatment setting⇅ drug group⇅ drug name⇅ if other, please specify⇅ number of SBRT courses⇅ intracranial / extracranial⇅ treated site⇅ If other treated site, please specify⇅ median/mean total RT dose [Gy]⇅ minimum total RT dose [Gy]⇅ maximum total RT dose [Gy]⇅ median/mean number of fractions⇅ minimum number of fractions⇅ maximum number of fractions⇅ median/mean dose per fraction [Gy]⇅ minimum dose per fraction [Gy]⇅ maximum dose per fraction [Gy]⇅ toxicity type⇅ patients with acute G>=3 toxicity⇅ patients with late G>=3 toxicity⇅ patients with G>=3 toxicity, timing unspecified⇅ G>=3 AEs⇅ patients with G>=3 AEs⇅ details on G>=3 toxicity⇅ details on G>=3 toxicity in RT field⇅
Lee et al. 2026 Prospective Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer 10.1016/j.esmoop.2025.106057 NCT05167851 33 Missing 23.1 Lung cancer oligometastatic EGFR targeting TKI Lazertinib — 33 both brain, lung, thoracic LN, other Missing Missing Missing Missing 5 and 3 3 and 1 15 and 5 7 and 8 3 and 5 10 and 20 Treatment-rel. — — 6 any G3-4: 7 AEs any G3-4: 6 pts
any G3-4: paresthesia, lipase increased, amylase increased
unknown