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Tislelizumab

Showing 1 study arm with grade ≥3 adverse event data (treatment-related and RT-related). Click a column header to sort.
Note on patient counts: some articles reported only percentages rather than absolute numbers. Where this occurred, the number of patients — including those with grade ≥3 adverse events — was derived by applying the reported percentage to the total arm size, which may produce a non-integer value. These figures have been rounded to the nearest integer for display.
1st Author⇅ Year⇅ Study Type⇅ Title⇅ DOI⇅ clinical trial number⇅ number of patients⇅ median/mean age⇅ median follow-up [months]⇅ tumor type⇅ treatment setting⇅ drug group⇅ drug name⇅ if other, please specify⇅ number of SBRT courses⇅ intracranial / extracranial⇅ treated site⇅ If other treated site, please specify⇅ median/mean total RT dose [Gy]⇅ minimum total RT dose [Gy]⇅ maximum total RT dose [Gy]⇅ median/mean number of fractions⇅ minimum number of fractions⇅ maximum number of fractions⇅ median/mean dose per fraction [Gy]⇅ minimum dose per fraction [Gy]⇅ maximum dose per fraction [Gy]⇅ toxicity type⇅ patients with acute G>=3 toxicity⇅ patients with late G>=3 toxicity⇅ patients with G>=3 toxicity, timing unspecified⇅ G>=3 AEs⇅ patients with G>=3 AEs⇅ details on G>=3 toxicity⇅ details on G>=3 toxicity in RT field⇅
Li et al. 2024 Prospective Neoadjuvant tislelizumab plus stereotactic body radiotherapy and adjuvant tislelizumab in early-stage resectable hepatocellular carcinoma: the Notable-HCC phase 1b trial 10.1038/s41467-024-47420-3 NCT05185531 20 58.5 6.1 HCC primary Anti-PD-(L)1 mAb Tislelizumab — 20 extra-cranial liver — 24 24 24 3 3 3 8 8 8 Treatment-rel. — — 8 any G3: 8 AE any G3: 8 pt
any G3: Lymphocyte count decrease, platelet count decrease, white blood cell decrease, aspartate aminotransferase increase, neutrophil count decrease, alanine aminotransferase increase
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